FANDOM


  • Autosomal dominant 遺傳疾病
  • Vogt's Triad
    1. Mental retardation
    2. Epilepsy
    3. Facial angiofibromas (Adenoma sebaceum)
  • Other cutaneous manifestation
    1. Shagreen patch in the lumbosacral region
    2. Ash-leaf hypomelonotic macules (earliest cutaneous sign)
    3. Skin fibroma
    4. Subungal and periungal fibroma
  • Other Systemic involvement
    1. Brain: subependymal giant cell astrocytomas, calcification
    2. Retinal hamartoma
    3. Renal angiomyolipoma
    4. Cardiac rhabdomyoma