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Thyroid Peroxidase (TPO) Antibody 編輯

  • The thyroid microsomal antigen has been shown to be the enzyme thyroid peroxidase (TPO)
  • Autoantibodies produced against TPO are capable of inhibiting the enzyme activity.

Clinical Significance: 編輯

  1. More than 90 percent of patients with autoimmune thyroiditis (Hashimoto's thyroiditis) have thyroglobulin or TPO antibodies.
  2. found in most patients with idiopathic hypothyroidism (85%) and Graves disease (50%)
  3. aid in predicting the progression of chronic thyroiditis

Reference Interval: 編輯

  • 0.0-2.0 IU/mL

Reference 編輯

  1. Thyroid Peroxidase (TPO) Antibody, ARUP's Guide to Clinical Laboratory Testing